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Gendepot/BIO, 6-Bromoindirubin-3′-Oxime , BC2001/1mg/BC2001-001
Gendepot/BIO, 6-Bromoindirubin-3′-Oxime , BC2001/1mg/BC2001-001
商品编号：
BC2001-001
品牌：
Gen depot
市场价：
¥1960.00
美元价：
1176.00
产品分类：
电生理设备
公司分类：
Electrophysiological
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| IC50 | 5 nM for GSK-3α/β in a cell-free assay, shows >16-fold selectivity over CDK5, also a pan-JAK inhibitor. |
|---|---|
| Target | β-catenin phosphorylation on GSK-3-specific sites |
| Solubility | The solubility of this compound in DMSO is >10 mM. General tips for obtaining a higher concentration: Please warm the tube at 37℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months. |
| Alternative Names | GSK-3α/GSK-3β inhibitor |
6-bromoindirubin-3′-oxime (BIO) is a potent, reversible and ATP-competitive GSK-3α/β inhibitor and the first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells. Human embryonic stem cells (hESCs) are maintained in the undifferentiated state through treatment with a GSK-3 inhibitor, BIO, under a feeder-free condition.
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