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当前位置: 首页 > 产品中心 > acidness > Gendepot/Bexarotene, Free acid, >99% , BC005/500 mg/BC005-500
商品详细Gendepot/Bexarotene, Free acid, >99% , BC005/500 mg/BC005-500
Gendepot/Bexarotene, Free acid,  >99% , BC005/500 mg/BC005-500
Gendepot/Bexarotene, Free acid, >99% , BC005/500 mg/BC005-500
商品编号: BC005-500
品牌: Gen depot
市场价: ¥4200.00
美元价: 2520.00
产地: 美国(厂家直采)
公司:
产品分类:
公司分类: acidness
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
TXRRXR
Solubility8 mg/mL (22.98 mM) in DMSO
Other NameTargretin, Targretyn,Targrexin , LGD-1069 , LG 1069 , LG100069 , SR-11247
Bexarotene is a highly selective retinoid X receptor (RXR) agonist. It is an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability. The activity in the mouse Alzheimer′s models are believed to be by activating PPARγ:RXR and LXR:RXR dimers which induces the expression of apoE and facilitates Aβ clearance and promotes microglial phagocytosis.
品牌介绍
Gendepot我们为您的自定义规模应用提供各种试剂,化合物,设备和树脂。我们的技术和定制的工作流程解决方案有助于扩展和补充生命科学工具提供商和应用市场的产品组合,例如分子诊断,疫苗生产,基于细胞的测定,大规模DNA / RNA纯化等。