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当前位置: 首页 > 产品中心 > Anti_Human > Gendepot/ADAM10, Human Recombinant Protein, CG1002/10 ug/CG1002-010
商品详细Gendepot/ADAM10, Human Recombinant Protein, CG1002/10 ug/CG1002-010
Gendepot/ADAM10, Human Recombinant Protein, CG1002/10 ug/CG1002-010
Gendepot/ADAM10, Human Recombinant Protein, CG1002/10 ug/CG1002-010
商品编号: CG1002-010
品牌: Gen depot
市场价: ¥3700.00
美元价: 2220.00
产地: 美国(厂家直采)
公司:
产品分类: 抗人
公司分类: Anti_Human
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
SourceEscherichia Coli.
FormulationThe ADAM10 solution contains 20mM Tris (pH 8), 1mM EDTA and 50% Glycerol.
PurityGreater than 95.0% as determined by SDS-PAGE.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
ADAM10 is part of the ADAM family which are cell surface proteins with a distinctive structure possessing both potential adhesion and protease domains. ADAM10 cleaves many proteins including TNF-alpha and E-cadherin. ADAM10 cleaves the membrane-bound precursor of tnf-alpha at 76- ala-|-val-77 to its mature soluble form. ADAM10 is in charge for the proteolytic release of several other cell-surface proteins, including ephrin-a2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein. ADAM10 is involved in the normal cleavage of the cellular prion protein. ADAM10 is involved in the cleavage of the adhesion molecule l1 at the cell surface and in the release of membrane vesicles, suggesting a vesicle-based protease activity. ADAM10 controls the proteolytic processing of notch and mediates lateral inhibition during neurogenesis.
品牌介绍
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