Type I collagen is a major structural component of skin, bone, tendon, and other fibrous connective tissues, and differs from other collagens by its low lysine hydroxylation and low carbohydrate composition. Although a number of types of collagen have been identified, all are composed of molecules containing three polypeptide chains arranged in a triple helical conformation. Slight differences in the primary structure (amino acid sequence) establish differences between the types.

This product is suitable for the preparation of collagen gels for the culture of human hematopoietic progenitor cells. This product can also be used to prepare collagen films (collagen coating) on cell culture surfaces.

The rate of gel formation, gel consistency and gel clarity may vary between lots. Agitation of the gel during formation, exposure to ultraviolet light and temperature extremes can influence the integrity of the gel.