Gendepot/紫杉醇>99.5%，BC063/500mg/BC063-500
市场价：
¥5900.00
美元价：
3540.00
产品分类：
电生理设备
公司分类：
Electrophysiological
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Assay | >99.5% |
|---|---|
| Solubility | DMSO: 50 mg/mL (can be stored frozen for several months) |
| Biochem/physiol Actions | Paclitaxel is a potent anti-neoplastic and anti-mitotic taxane drug, which binds to the N-terminus of β-tubulin and and stabilizes microtubules arresting the cell cycle at the G2/M phase. The microtubule damage induces apoptosis through a JNK-dependent pathway followed by a JNK-independent pathway, perhaps related to the activation of protein kinase A (PKA) or of Raf-1 kinase, resulting in phosphorylation of Bcl-2. A major metabolite via CYP2CB is 6α-hydroxypaclitaxel (6α-OHP). |
Paclitaxel is an antitumor agent. Stabilizes microtubules and lowers the critical concentration for tubulin polyerization. Reversibly binds to polyerized tubulin.mInhibits protein isoprenylation and induces apoposis in PC-3 human prostatemcancer cells.
The checkpoint of mitotic spindle assembly, aberrant activation ofmcyclin-dependent kinases (CKDs) and the c-Jun N-terminal/stress activated protein
kinase (JNK/SAPK) are involved in Paclitaxel-induced apoptosis.
品牌介绍
Gendepot我们为您的自定义规模应用提供各种试剂，化合物，设备和树脂。我们的技术和定制的工作流程解决方案有助于扩展和补充生命科学工具提供商和应用市场的产品组合，例如分子诊断，疫苗生产，基于细胞的测定，大规模DNA / RNA纯化等。
品牌分类
生化试剂
Protein Biochemistry Reagent
蛋白质电泳试剂
抗体
Peptide
实验室必备耗材
Cell Based Assay Kit
Microbiology Reagent
生物分子
DNA Electrophoresis Reagent
IHC Kit and Reagent
蛋白质分离纯化
植物培养
Cell/Tissue Culture
Cloning Reagent
Lab Essential Equipment
Cytokines
分析试剂盒
Biological Buffers
Growth Factor
IP & Reagent
分子生物学试剂
DNA/RNA纯化试剂
Enzymes
ELISA试剂盒和试剂
PCR/RT-PCR Reagent
Protein Assay Reagent
Immunochemical Reagent
蛋白质印迹试剂
转染试剂
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